Let me preface this by saying it has only begun happening on osx 10.7 and 10.8. My laptop running 10.6 has never had this issue.
So I've had this issue before while freelancing - Periodically, and for reasons that I've been entirely unable to pin down, Extendscript Toolkit (the one that ships with CS6) will for all intents and purposes cease functioning. I've been thick in editing code when I realize that it pretends to be working, but fails to run the code or even respond to keyboard shortcuts.
Command-R does nothing, Command-C / Command-V do nothing.
Hilariously, Command-S does nothing. There are plenty of times where I have to manually drag-select my entire code and right click to copy it out into a different text editor to save my work.
Thankfully, Command-Q still works.
I'm really at a loss here. In the past I've resorted to running my code via applescript, ft-toolbar, etc etc. This leaves me working in the dark without access to a debugger. Nothing spells fun like putting all your debugging info into an alert(). Until I can resolve this issue, I just have to drag my laptop with me when I freelance and use it to write all my code.
The only thing that I thought could cause it was 'enable javascript debugger' in the general prefs but that seems to have no effect.
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Okay, I went and removed everything from 'startup' and changed some random preferences in EST. (I always like to sanity check before asking questions on the internet) and LO AND BEHOLD, it seems to be working, after two weeks of not working.
I'd still deeply appreciate any and all insight into this issue, as it has already severely taxed my sanity.
Andrew